[HTML][HTML] Ex vivo expansion of human peripheral blood natural killer cells and cytotoxic T lymphocytes from lung cancer patients

HTM Nhung, BV Anh, TL Huyen… - Oncology …, 2018 - spandidos-publications.com
… NK cells directly kill target tumor cells through the apoptosis mechanism by releasing
cytoplasmic granules containing perforin and granzymes, or by expressing death receptor ligands …

Development of anti-human mesothelin-targeted chimeric antigen receptor messenger RNA–transfected peripheral blood lymphocytes for ovarian cancer therapy

CF Hung, X Xu, L Li, Y Ma, Q Jin, A Viley… - Human gene …, 2018 - liebertpub.com
… ex vivo selected, activated, and expanded T cells/natural killer cells into preclinical models
and human clinical trials targeting multiple tumor-associated antigens for both hematological …

Emerging insights into natural killer cells in human peripheral tissues

NK Björkström, HG Ljunggren… - Nature Reviews …, 2016 - nature.com
… and, thereby, enable NK cells to target cells lacking self-HLA class I … egress of lymphocytes
from tissues into the blood through its … of CD103 on human peripheral blood NK cells 66 and …

[HTML][HTML] The emerging role of off-the-shelf engineered natural killer cells in targeted cancer immunotherapy

KP Fabian, JW Hodge - Molecular Therapy-Oncolytics, 2021 - cell.com
Natural killer (NK) cells are innate lymphocytes that recognize and clear infected and
transformed … LAK cells were generated from freshly isolated peripheral blood mononuclear …

Targeting natural killer cells in solid tumors

G Habif, A Crinier, P André, E Vivier… - Cellular & molecular …, 2019 - nature.com
… In human peripheral blood, NK cells are defined as CD14 − CD19 − CD3 − and can be … 1
(KLRG1), cytotoxic T lymphocyte antigen 4 (CTLA4) and lymphocyte activation gene 3 protein (…

[HTML][HTML] The biological effects of polystyrene nanoplastics on human peripheral blood lymphocytes

DK Sarma, R Dubey, RM Samarth, S Shubham… - Nanomaterials, 2022 - mdpi.com
… particles on human cells. To address this gap, we aimed to assess the genotoxic and
cytotoxic potential of PSNPs with a size of 50 nm in human peripheral blood lymphocyte cells. …

[HTML][HTML] Brain ischemia significantly alters microRNA expression in human peripheral blood natural killer cells

Y Kong, S Li, X Cheng, H Ren, B Zhang, H Ma… - Frontiers in …, 2020 - frontiersin.org
… miRNAs that were altered after acute ischemic stroke, many are predicted to regulate a
number of target genes and pathways associated with lymphocyte activation, mobilization, and …

[HTML][HTML] Natural killer cells for immunotherapy–advantages of the NK-92 cell line over blood NK cells

H Klingemann, L Boissel, F Toneguzzo - Frontiers in immunology, 2016 - frontiersin.org
… obtained from the peripheral blood of either the patient (… 10% of circulating blood lymphocytes
are NK cells: to collect … CXCR2 is responsible for targeting cytotoxic cells to solid tumors (…

CD57 in human natural killer cells and T-lymphocytes

H Kared, S Martelli, TP Ng, SLF Pender… - Cancer Immunology …, 2016 - Springer
… For this reason, researchers have focused their efforts on investigating the expression and
… , cytotoxic, and inflammatory NK cells was similar to that observed in peripheral blood from …

Multiwall carbon nanotube-induced DNA damage and cytotoxicity in male human peripheral blood lymphocytes

JS Kim, KS Song, IJ Yu - International journal of toxicology, 2016 - journals.sagepub.com
… to target cells and … human peripheral blood lymphocytes (HPBLs), yet toxicological studies
on the effect of MWCNTs on HPBLs are lacking. Accordingly, this study evaluated the cytotoxic